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Notify individuals that: Tramadol Hydrochloride Prolonged-Release is for oral use only and should be swallowed entire. The capsule really should not be chewed, dissolved, crushed or break up. Tramadol Hydrochloride Prolonged-Launch may perhaps induce seizures and/or serotonin syndrome with concomitant utilization of serotonergic agents (like SRIs,